Alpha-fetoprotein (AFP)

CAT: 0209-101-M104Size: 50 µgDry Ice: NoHazardous: No
CAT#:0209-101-M104Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Alpha-1-fetoprotein (AFP), also alphafoetoprotein or α1-foetoprotein, is a glycoprotein in mammals that is produced during human embryonic development in the course of pregnancy by the entodermal tissue and fetal liver, or in adults especially in tumor cells of the liver. Physiologically, alpha-1 fetoprotein has the function of a fetal transport protein, particularly transporting copper, nickel, fatty acids, and bilirubin in fetal blood plasma. AFP is structurally closely related to the transport proteins albumin, vitamin D-binding protein, and afamine. Production begins in the four-week-old embryo, is highest in the twelfth to sixteenth weeks, and stops almost completely after birth. In the adult, plasma levels are usually less than 40 ng/ml.
Synonyms
Alpha-1-fetoprotein, Alpha-fetoglobulin
NCBI Gene ID
174
UniProt
P02771
Accession Number
NP_001125.1
Accession Number mRNA
NM_001134.2
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Purified human native Alpha-fetoprotein (AFP) protein
Clone
(#5E47)
Applications
E
Purification Method
Protein G chromatography
Assay Protocol
Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG1

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