Eotaxin-2 (CCL24) Recombinant Protein

Eotaxin-2 (CCL24) Recombinant Protein

• Description: Eotaxin-2 is a CC chemokine that signals through the CCR3 receptor. It is produced by activated monocytes and T lymphocytes. Eotaxin-2 selectively chemo attracts cells expressing CCR3 including eosinophils, basophils, Th2 T cells, mast cells, and certain subsets of dendritic cells. Additionally, Eotaxin-2 inhibits the proliferation of multi potential hematopoietic progenitor cells. The mature protein, which also includes a C-terminal truncation, contains 78 amino acid residues (92 a.a. residues for the murine homolog, without C-terminal truncation). Recombinant human Eotaxin-2 is an 8.8 kDa protein containing 78 amino acid residues.
• Synonyms: CCL24; Ckb-6; MPIF2; MPIF-2; SCYA24
• CAS Number: 9000-83-3
• NCBI Gene ID: 6369
• UniProt: O00175
• Accession Number: NP_002982.2
• Accession Number mRNA: NM_002991
• Gene Location: 7q11.23
• Host: E. coli
• Origin Species: Human
• Species Reactivity: Mouse, Human, Bacteria
• Sequence: VVIPSPCCMF FVSKRIPENR VVSYQLSSRS TCLKGGVIFT TKKGQQFCGD PKQEWVQRYM KNLDAKQKKA SPRARAVA
• Detection Range: Determined by its ability to chemoattract using human peripheral blood eosinophils using a concentration of 50-100 ng/ml.
• Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
• Purity: > 98% by SDS-PAGE & HPLC analyses
• Length: 78
• Form: Lyophilized
• Molecular Weight: 8.8 kDa
• Shipping Conditions: Room Temperature