Eotaxin-2 Recombinant Protein

Eotaxin-2 Recombinant Protein

• Description: Eotaxin-2 is a CC chemokine that signals through the CCR3 receptor. It is produced by activated monocytes and T lymphocytes. Eotaxin-2 selectively chemoattracts cells expressing CCR3 including eosinophils, basophils, Th2 T cells, mast cells, and certain subsets of dendritic cells. Additionally, Eotaxin-2 inhibits the proliferation of multipotential hematopoietic progenitor cells. The mature protein, which also includes a C-terminal truncation, contains 78 amino acid residues (92 a.a. residues for the murine homolog, without C-terminal truncation). Recombinant murine Eotaxin-2 is an 10.3 kDa protein containing 93 amino acid residues.
• Synonyms: Ccl24; CKb-6; MPIF-2; Scya24
• CAS Number: 9000-83-3
• NCBI Gene ID: 56221
• UniProt: Q9JKC0
• Accession Number: NP_062523.1
• Accession Number mRNA: NM_019577
• Gene Location: 5; 5 G1
• Host: E. coli
• Origin Species: Mouse
• Species Reactivity: Mouse, Human
• Sequence: VTIPSSCCTS FISKKIPENR VVSYQLANGS ICPKAGVIFI TKKGHKICTD PKLLWVQRHI QKLDAKKNQP SKGAKAVRTK FAVQRRRGNS TEV
• Detection Range: Determined by its ability to chemoattract murine lymphocytes using a concentration range of 10-100 ng/ml
• Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
• Purity: > 98% by SDS-PAGE & HPLC analyses
• Length: 93
• Form: Lyophilized
• Molecular Weight: 10.3 kDa
• Shipping Conditions: Room Temperature