Eotaxin-3 (CCL26) Recombinant Protein

Eotaxin-3 (CCL26) Recombinant Protein

• Description: Eotaxin-3 is a CC chemokine that signals through the CCR3 receptor. It is produced by endothelial cells stimulated with IL-4 or IL-13. Eotaxin-3 selectively targets cells expressing CCR3, including eosinophils, basophils, T cells and monocytes. Eotaxin-3 has similar activity to Eotaxin and Eotaxin-2, but the three Eotaxins share only a low degree of sequence homology. Recombinant human Eotaxin-3 is an 8.4 kDa protein containing 71 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.
• Synonyms: CCL26; IMAC; TSC-1; MIP-4a; SCYA26; MIP-4alpha
• CAS Number: 9000-83-3
• NCBI Gene ID: 10344
• UniProt: Q9Y258
• Accession Number: NP_006063
• Accession Number mRNA: NM_006072
• Gene Location: 7q11.23
• Host: E. coli
• Origin Species: Human
• Species Reactivity: Human
• Sequence: TRGSDISKTC CFQYSHKPLP WTWVRSYEFT SNSCSQRAVI FTTKRGKKVC THPRKKWVQK YISLLKTPKQ L
• Detection Range: Determined by its ability to chemoattract human CCR3/HEK 293 cells. The maximum activity was achieved at 2 µg/ml.
• Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
• Purity: > 98% by SDS-PAGE & HPLC analyses
• Length: 71
• Form: Lyophilized
• Molecular Weight: 8.4 kDa
• Shipping Conditions: Room Temperature