Endostatin Recombinant Protein

CAT:

209-100-334

Size:

100 µg

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Description: Endostatin is a naturally occurring 20 kDa polypeptide derived from the C-terminal portion of type XVIII collagen. It functions as an anti-angiogenic cytokine that is expressed in various organs with the highest levels in liver, lung and kidney. Endostatin inhibits angiogenesis by blocking the pro-angiogenic activities of VEGF and FGF-basic. Recombinant human Endostatin is a 20.2 kDa protein consisting 184 amino acid residues.
Synonyms: COL18A1; KS; KNO; KNO1
CAS Number: 9000-83-3
NCBI Gene ID: 80781
UniProt: P39060
Accession Number: NP_085059
Accession Number mRNA: NM_030582
Gene Location: 21q22.3
Host: E. coli
Origin Species: Human
Species Reactivity: Human
Sequence: MHSHRDFQPV LHLVALNSPL SGGMRGIRGA DFQCFQQARA VGLAGTFRAF LSSRLQDLYS IVRRADRAAV PIVNLKDELL FPSWEALFSG SEGPLKPGAR IFSFDGKDVL RHPTWPQKSV WHGSDPNGRR LTESYCETWR TEAPSATGQA SSLLGGRLLG QSAASCHHAY IVLCIENSFM TASK
Detection Range: Measured by its ability to inhibit HUVEC migration.
Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
Purity: 98% by SDS-PAGE & HPLC analyses
Length: 184
Form: Lyophilized
Molecular Weight: 20.2 kDa
Shipping Conditions: Room Temperature

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