Endostatin Recombinant Protein
CAT:
209-100-334
Size:
100 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Endostatin Recombinant Protein
- Description: Endostatin is a naturally occurring 20 kDa polypeptide derived from the C-terminal portion of type XVIII collagen. It functions as an anti-angiogenic cytokine that is expressed in various organs with the highest levels in liver, lung and kidney. Endostatin inhibits angiogenesis by blocking the pro-angiogenic activities of VEGF and FGF-basic. Recombinant human Endostatin is a 20.2 kDa protein consisting 184 amino acid residues.
- Synonyms: COL18A1; KS; KNO; KNO1
- CAS Number: 9000-83-3
- NCBI Gene ID: 80781
- UniProt: P39060
- Accession Number: NP_085059
- Accession Number mRNA: NM_030582
- Gene Location: 21q22.3
- Host: E. coli
- Origin Species: Human
- Species Reactivity: Human
- Sequence: MHSHRDFQPV LHLVALNSPL SGGMRGIRGA DFQCFQQARA VGLAGTFRAF LSSRLQDLYS IVRRADRAAV PIVNLKDELL FPSWEALFSG SEGPLKPGAR IFSFDGKDVL RHPTWPQKSV WHGSDPNGRR LTESYCETWR TEAPSATGQA SSLLGGRLLG QSAASCHHAY IVLCIENSFM TASK
- Detection Range: Measured by its ability to inhibit HUVEC migration.
- Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
- Purity: 98% by SDS-PAGE & HPLC analyses
- Length: 184
- Form: Lyophilized
- Molecular Weight: 20.2 kDa
- Shipping Conditions: Room Temperature