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CXCR4

CAT: 0209-102-PA120Size: 200 µgDry Ice: NoHazardous: No
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CAT#:0209-102-PA120Size:200 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CXCR4, also known as fusin, is a 7TM G protein-linked chemokine receptor. CXCR4 is expressed on B cells, monocytes, CD4+ T cells, colonic epithelial cells, and astrocytes and binds SDF1/ CXCL12. CXCR4 is upregulated on mammary tumors. CXCR4, in cooperation with CD134 and heparan sulfate proteoglycans, functions as a coreceptor for feline immunodeficiency virus (FIV) entry into cells. Feline CXCR4 shares 97%, 95%, 88%, and 90% aa sequence identity with canine, human, mouse, and rat CXCR4, respectively.
Synonyms
CXCR4; FB22; HM89; LAP3; LCR1; NPYR; WHIM; CD184; LESTR; NPY3R; NPYRL; HSY3RR; NPYY3R; D2S201E
NCBI Gene ID
7852
UniProt
P61073
Accession Number
NP_001008540.1
Accession Number mRNA
NM_001008540.1
Chromosomal Location
2q21
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human CXCR4 fusion protein [N-terminal and loops]
Clone
Rabbit IgG
Applications
WB, E
Purification Method
Protein A purified
Assay Protocol
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Bioactivity
Western Blot: Use 2-5 µg/ml
Form
Lyophilized
Buffer
PBS
Reconstitution
Water
Storage Conditions
The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
Host or Source
Rabbit

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