CXCL4 (PF-4)

• Description:

  PF-4 or CXCL-4 is a CXC chemokine that is expressed in megakaryocytes and stored in the α-granules of platelets. PF-4 is chemotactic towards neutrophils and monocytes and has been shown to inhibit angiogenesis. Recombinant human PF-4 is a 7.8 kDa protein containing 70 amino acid residues, including the four highly conserved residues present in CXC chemokines.

• Synonyms:

  PF4; PF-4; CXCL4; SCYB4

• NCBI Gene ID:

  5196

• UniProt:

  P02776

• Accession Number:

  NP_002610.1

• Accession Number mRNA:

  NM_002619.2

• Chromosomal Location:

  4q12-q21

• Reactivity:

  Anti-Human

• Cross Reactivity:

  Human

• Target Antigen:

  Human recombinant CXCL4

• Clone:

  (#6R37)

• Applications:

  ICC, Capture AB

• Purification Method:

  Protein G chromatography

• Assay Protocol:

  Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Bioactivity:

  ICC (1 to 50-100)

• Form:

  Lyophilized

• Buffer:

  PBS

• Reconstitution:

  PBS

• Storage Conditions:

  Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

• Host or Source:

  Mouse

• Isotype:

  IgG2