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Common gamma chain (IL-2R)

CAT: 0209-101-M334Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M334Size:100 µg
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Description
When IL-2 R alpha is associated with the IL-2 receptor beta and gamma chains, a high affinity heterotrimeric receptor complex that transduces IL-2 signals is formed. The gamma chain is also the common signaling subunit of the high affinity receptor complex for IL-2, IL-4, IL-7, IL-9, IL-15 and IL-21.
Synonyms
Common gamma chain
NCBI Gene ID
3561
UniProt
P31785
Accession Number
NP_000197.1
Accession Number mRNA
NM_000206.2
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Human recombinant Common gamma chain
Clone
(#7A23)
Applications
WB, N
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG1

UniProtKB · P31785

Cytokine receptor common subunit gamma

IL2RG_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P31785
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
IL2RG
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
Q5FC12
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneMembrane

Disease

Disease variantSCID

PTM

Disulfide bondGlycoproteinPhosphoprotein

Biological process

Host-virus interaction

Molecular function

Receptor

Domain

SignalTransmembraneTransmembrane helix

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