Coagulation Factor X

• Description:

  Coagulation Factor X is a vitamin K-dependent plasma protease that activates thrombin in blood coagulation. Initially synthesized in the liver as a single-chain precursor, factor X is activated by both the intrinsic and extrinsic pathways to Xa, which consists of disulfide bond-linked light and heavy chains. The light chain contains a Gla and two EGF-like domains and the heavy chain corresponds to the serine protease domain.

• Synonyms:

  F10; FX; FXA

• NCBI Gene ID:

  2159

• UniProt:

  P00742

• Accession Number:

  NP_000495.1

• Accession Number mRNA:

  NM_000504.3

• Chromosomal Location:

  13q34

• Reactivity:

  Anti-Human

• Cross Reactivity:

  Human

• Target Antigen:

  Human recombinant Coagulation factor X

• Clone:

  (#10A10)

• Applications:

  WB

• Purification Method:

  Protein G chromatography

• Assay Protocol:

  Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form:

  Lyophilized

• Buffer:

  PBS

• Reconstitution:

  PBS

• Storage Conditions:

  Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

• Host or Source:

  Mouse

• Isotype:

  IgG1