Coagulation Factor III (Tissue Factor)

• Description :

  Coagulation factor III is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as non-functional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces, for example, on monocytes.

• Synonyms :

  Coagulation factor III, Thromboplastin, CD142

• NCBI Gene ID :

  2152

• UniProt :

  P13726

• Accession Number :

  NP_001171567.1

• Accession Number mRNA :

  NM_00118096.1

• Reactivity :

  Anti-Human

• Cross Reactivity :

  Human

• Target Antigen :

  Recombinant human Coagulation Factor III (Tissue Factor)

• Clone :

  (#21U4)

• Applications :

  WB, IP, Capture Ab

• Purification Method :

  Protein G chromatography

• Assay Protocol :

  Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form :

  Lyophilized

• Buffer :

  PBS

• Reconstitution :

  PBS

• Storage Conditions :

  Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.

• Host or Source :

  Mouse

• Isotype :

  IgG2