Coagulation Factor III (Tissue Factor)

• Description:

  Coagulation factor III is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as non-functional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces, for example, on monocytes.

• Synonyms:

  Coagulation factor III, Thromboplastin, CD142

• NCBI Gene ID:

  2152

• UniProt:

  P13726

• Accession Number:

  NP_001171567.1

• Accession Number mRNA:

  NM_00118096.1

• Reactivity:

  Anti-Human

• Cross Reactivity:

  Human

• Target Antigen:

  Recombinant human Coagulation Factor III (Tissue Factor)

• Clone:

  (#21U4)

• Applications:

  WB, IP, Capture Ab

• Purification Method:

  Protein G chromatography

• Assay Protocol:

  Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form:

  Lyophilized

• Buffer:

  PBS

• Reconstitution:

  PBS

• Storage Conditions:

  Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.

• Host or Source:

  Mouse

• Isotype:

  IgG2