CD105/Endoglin

• Description:

  The MJ7/18 monoclonal antibody reacts with the mouse CD105 molecule, also known as Endoglin. This 90 kDa disulfide-linked homodimer is expressed by vascular endothelial cells. It is suggested that CD105 functions in adhesion and embryonic angiogenesis.

• Synonyms:

  Eng endoglin; CD105; AI528660; AI662476; S-endoglin

• NCBI Gene ID:

  13805

• UniProt:

  Q63961

• Accession Number:

  NP_031958

• Accession Number mRNA:

  NM_007932

• Chromosomal Location:

  2 B; 2 21.4 cM

• Reactivity:

  Anti-Mouse

• Cross Reactivity:

  Mouse

• Target Antigen:

  Inflamed mouse skin

• Clone:

  (#MJ7/18)

• Applications:

  WB, IHC (F), IP, FC

• Purification Method:

  Protein G chromatography

• Assay Protocol:

  Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.

• Bioactivity:

  Western Blot: use at 1-5 µg/ml.

• Form:

  Lyophilized

• Buffer:

  PBS

• Reconstitution:

  Water

• Storage Conditions:

  The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.

• Host or Source:

  Rat

• Isotype:

  IgG2a