CD86

• Description :

  CD86 is an 80 kD immunoglobulin superfamily member, also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells and astrocytes. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production.

• Synonyms :

  B7-2; B70; Ly-58

• NCBI Gene ID :

  12524

• UniProt :

  P42082

• Accession Number :

  NP_062261.3

• Accession Number mRNA :

  NM_019388.3

• Chromosomal Location :

  16 B5; 16 26.9 cM

• Reactivity :

  Anti-Mouse

• Cross Reactivity :

  Mouse

• Target Antigen :

  LPS stimulated Mouse B-Cells

• Clone :

  (#MAB0803)

• Applications :

  https://www.reliatech.de/pub/media/ds/ma/103-M150.pdf

• Purification Method :

  Protein G/A chromatography

• Assay Protocol :

  Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form :

  Lyophilized

• Buffer :

  PBS

• Reconstitution :

  PBS (sterile)

• Storage Conditions :

  Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

• Host or Source :

  Rat

• Isotype :

  IgG2