CD86

• Description:

  CD86 is an 80 kD immunoglobulin superfamily member, also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells and astrocytes. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production.

• Synonyms:

  B7-2; B70; Ly-58

• NCBI Gene ID:

  12524

• UniProt:

  P42082

• Accession Number:

  NP_062261.3

• Accession Number mRNA:

  NM_019388.3

• Chromosomal Location:

  16 B5; 16 26.9 cM

• Reactivity:

  Anti-Mouse

• Cross Reactivity:

  Mouse

• Target Antigen:

  LPS stimulated Mouse B-Cells

• Clone:

  (#MAB0803)

• Applications:

  https://www.reliatech.de/pub/media/ds/ma/103-M150.pdf

• Purification Method:

  Protein G/A chromatography

• Assay Protocol:

  Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form:

  Lyophilized

• Buffer:

  PBS

• Reconstitution:

  PBS (sterile)

• Storage Conditions:

  Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

• Host or Source:

  Rat

• Isotype:

  IgG2