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BD-5

CAT: 0209-102-P99Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-102-P99Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The alpha-defensins are distinguished from the beta-defensins by the pairing of their three disulfide bonds. To date, six human beta-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The beta-defensin proteins are expressed as the C-terminal portion of precursors, and are released by proteolytic cleavage of a signal sequence and, in some cases, a propeptide sequence. Beta-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds.
Synonyms
BD5, DEFB5, DEFB105a, Beta-Defensin 5
NCBI Gene ID
245908
UniProt
Q8NG35
Accession Number
NP_689463.1
Accession Number mRNA
NM_152250.2
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
E.coli derived Recombinant Human BD-5
Clone
Rabbit IgG
Applications
ELISA, WB
Purification Method
Antigen-affinity purified
Assay Protocol
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
Water
Storage Conditions
The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.
Host or Source
Rabbit

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