BD-5 Antibody

• Background :

  Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The alpha-defensins are distinguished from thebeta-defensins by the pairing of their three disulfide bonds. To date, six humanbeta-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The beta-defensin proteins are expressed as the C-terminal portion of precursors, and are released by proteolytic cleavage of a signal sequence and, in some cases, a propeptide sequence. beta-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. Recombinant Human BD-5 is a 5.8 kDa protein containing 51 amino acid residues

• NCBI Gene ID :

  245908

• Swiss Prot :

  Q8NG35

• Accession Number :

  Q8NG35

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hBD-5. Anti-Human BD-5 specific antibody was purified by affinity chromatography employing immobilized hBD-5 matrix.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies, Antibody Pairs

• Field of Research :

  Chemokines & Cytokines, Immunology

• Purification :

  BD-5 specific antibody was purified by affinity chromatography employing immobilized hBD-5 matrix

• Concentration :

  Batch dependent

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Antibody is stable for at least 2 years from date of receipt at -20˚ C. The reconstituted antibody is stable for at least two weeks at 2-8˚ C. Frozen aliquots are stable for at least 6 months when stored at -20˚ C. Avoid repeated freeze-thaw cycles.

• Symbol :

  DEFB105A

• NCBI Official Name :

  Defensin beta 105A

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  BD5, DEFB5, DEFB105a, Beta-Defensin 5

• Tested Applications :

  ELISA, WB

• Protein ID :

  Q8NG35.1

• Physical Properties :

  Lyophilized

• CAS Number :

  9007-83-4