Gallic aldehyde

• Description:

  Gallic aldehyde (3,4,5-Trihydroxybenzaldehyde) is a phenolic aldehyde. Gallic aldehyde can be isolated from Geum japonicum. Gallic aldehyde inhibits the gelatinolytic activity and expression of MMP-9. Gallic aldehyde also inhibits ERK1/2, p38, and JNK. Gallic aldehyde has potent anti-HSV-1 and antioxidant activities. Gallic aldehyde also exhibits antibacterial activity against Oenococcus oeni VF[1][2][3][4].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  ERK; HSV; JNK; MMP; p38 MAPK

• Type:

  Reference compound

• Related Pathways:

  Anti-infection; MAPK/ERK Pathway; Metabolic Enzyme/Protease; Stem Cell/Wnt

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/gallic-aldehyde.html

• Purity:

  99.95

• Solubility:

  DMSO : 116.67 mg/mL (ultrasonic)

• Smiles:

  O=CC1=CC(O)=C(O)C(O)=C1

• Molecular Formula:

  C7H6O4

• Molecular Weight:

  154.12

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Kadota S, et al. A New Hydrolyzable Tannin from Geum japonicum and Its Antiviral Activity[J]. Heterocycles, 1994, 38 (1) :167-175.|[2]Miwa H, et al. Liquid chromatographic determination of free and total fatty acids in milk and milk products as their 2-nitrophenylhydrazides. J Chromatogr. 1990 Dec 7;523:235-46. |[3]Thomas SC, et al. Phytotoxicity and hormesis in common mobile organic compounds in leachates of wood-derived biochars. Biochar. 2024;6 (1) :51. |[4]Arturo Anadon, et al. EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF) ; Scientific Opinion on Flavouring Group Evaluation 06, Revision 2 (FGE.06Rev2) : Straight- and branched-chain aliphatic unsaturated primary alcohols, aldehydes, carboxylic acids, and esters from chemical groups 1 and 4. EFSA Journal 2011; 9 (3) :1844. [78 pp.].

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, stored under nitrogen)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  ERK1; ERK2; MMP-9

• CAS Number:

  [13677-79-7]