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Gallic acid

CAT: 0804-HY-N0523-01Size: 10 mM - 1 mLDry Ice: NoHazardous: No
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CAT#:0804-HY-N0523-01Size:10 mM - 1 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Gallic acid (3,4,5-Trihydroxybenzoic acid) is a natural polyhydroxyphenolic compound and an free radical scavenger to inhibit cyclooxygenase-2 (COX-2) [1]. Gallic acid has various activities, such as antimicrobial, antioxidant, antimicrobial, anti-inflammatory, and anticance activities[2].
CAS Number
149-91-7
Product Name Alternative
3,4,5-Trihydroxybenzoic acid
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Apoptosis; COX; Endogenous Metabolite; Ferroptosis; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Gallic_acid.html
Concentration
10mM
Purity
99.99
Solubility
DMSO : ≥ 100 mg/mL|H2O : 8.33 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(O)C1=CC(O)=C(O)C(O)=C1
Molecular Formula
C7H6O5
Molecular Weight
170.12
Precautions
H315, H319, H335
References & Citations
[1]Amaravani M, et al. COX-2 structural analysis and docking studies with gallic acid structural analogues. Springerplus. 2012 Dec;1 (1) :58.|[2]Bak EJ, et al. Gallic acid improves glucose tolerance and triglyceride concentration in diet-induced obesity mice. Scand J Clin Lab Invest. 2013 Dec;73 (8) :607-14.|[3]Cheng Y, et al. Plant Natural Products Calycosin and Gallic Acid Synergistically Attenuate Neutrophil Infiltration and Subsequent Injury in Isoproterenol-Induced Myocardial Infarction: A Possible Role for Leukotriene B4 12-Hydroxydehydrogenase? Oxid Med Cell Longev. 2015;2015:434052.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
COX-2; Human Endogenous Metabolite; Microbial Metabolite

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CatalogName
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