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Gallic acid (hydrate)

CAT: 0804-HY-N0523A-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N0523A-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Gallic acid (3,4,5-Trihydroxybenzoic acid) hydrate is a natural polyhydroxyphenolic compound and an free radical scavenger to inhibit cyclooxygenase-2 (COX-2) [1]. Gallic acid hydrate has various activities, such as antimicrobial, antioxidant, antimicrobial, anti-inflammatory, and anticance activities[2].
CAS Number
5995-86-8
Product Name Alternative
3,4,5-Trihydroxybenzoic acid (hydrate)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; COX; Endogenous Metabolite; Ferroptosis; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/gallic-acid-hydrate.html
Purity
99.99
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(O)C1=CC(O)=C(O)C(O)=C1.O
Molecular Formula
C7H8O6
Molecular Weight
188.13
Precautions
H302, H315, H319, H335
References & Citations
[1]Felipe Hugo Alencar Fernandes, et al. Gallic Acid: Review of the Methods of Determination and Quantification. Crit Rev Anal Chem|[2]Amaravani M, et al. COX-2 structural analysis and docking studies with gallic acid structural analogues. Springerplus. 2012 Dec;1 (1) :58.|[3]Bak EJ, et al. Gallic acid improves glucose tolerance and triglyceride concentration in diet-induced obesity mice. Scand J Clin Lab Invest. 2013 Dec;73 (8) :607-14.|[4]Cheng Y, et al. Plant Natural Products Calycosin and Gallic Acid Synergistically Attenuate Neutrophil Infiltration and Subsequent Injury in Isoproterenol-Induced Myocardial Infarction: A Possible Role for Leukotriene B4 12-Hydroxydehydrogenase? Oxid Med Cell Longev. 2015;2015:434052.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
COX-2; Microbial Metabolite

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