C8AP2 rabbit pAb

CAT: 0855-ES17928-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES17928-01Size:50 µL
Selected
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Nov 2008]
Description
This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Nov 2008],
UniProt
Q9UKL3
Swiss Prot
Q9UKL3
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human C8AP2 AA range: 1155-1205
Target
C8AP2
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:500-2000
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Cytoplasm. Nucleus. Nucleus, PML body. Mitochondrion. Exported from the nucleus to the mitochondria upon FAS activation.
Gene ID (Human)
9994

Popular Products