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Lapatinib (Standard)

CAT: 0804-HY-50898R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-50898R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Lapatinib (Standard) is the analytical standard of Lapatinib. This product is intended for research and analytical applications. Lapatinib (GW572016) is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively[1].
CAS Number
231277-92-2
Product Name Alternative
GW572016 (Standard) ; GW2016 (Standard)
UNSPSC
12352005
Target
Autophagy; EGFR; Ferroptosis; Reference Standards
Type
Reference Standards
Related Pathways
Apoptosis; Autophagy; JAK/STAT Signaling; Others; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lapatinib-standard.html
Smiles
O=S(CCNCC1=CC=C(C2=CC=C3C(C(NC4=CC(Cl)=C(C=C4)OCC5=CC(F)=CC=C5)=NC=N3)=C2)O1)(C)=O
Molecular Formula
C29H26ClFN4O4S
Molecular Weight
581.06
References & Citations
[1]Rusnak DW, et al. The effects of the novel, reversible epidermal growth factor receptor/ErbB-2 tyrosine kinase inhibitor, GW2016, on the growth of human normal and tumor-derived cell lines in vitro and in vivo. Mol Cancer Ther. 2001 Dec;1 (2) :85-94
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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