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CXCL2 rabbit pAb

CAT: 0855-ES20286-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES20286-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Function:Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta (5-73) shows a highly enhanced hematopoietic activity., online information:CXCL2 entry, pharmaceutical:GRO-beta (5-73) is available under the name Garnocestim as immunomodulator. It is used prior to hematopoietic transplantation for peripheral blood stem cell mobilization and reduction of incidence, duration, and/or severity of chemotherapy induced cytopenias., PTM:The N-terminal processed form GRO-beta (5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells., similarity:Belongs to the intercrine alpha (chemokine CxC) family.
Description
Function: Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta (5-73) shows a highly enhanced hematopoietic activity. online information: CXCL2 entry, pharmaceutical: GRO-beta (5-73) is available under the name Garnocestim as immunomodulator. It is used prior to hematopoietic transplantation for peripheral blood stem cell mobilization and reduction of incidence, duration, and/or severity of chemotherapy induced cytopenias. PTM: The N-terminal processed form GRO-beta (5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells. similarity: Belongs to the intercrine alpha (chemokine CxC) family.
UniProt
P19875
Swiss Prot
P19875
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human GROβ AA range: 58-107
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:1000-2000 ELISA 1:5000-20000
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Secreted.
Other Product Names
C-X-C motif chemokine 2 (Growth-regulated protein beta; Gro-beta; Macrophage inflammatory protein 2-alpha; MIP2-alpha) [Cleaved into: GRO-beta (5-73; GRO-beta-T; Hematopoietic synergistic factor; HSF; SB-251353) ]
Gene ID (Human)
2920

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