CXCL2 rabbit pAb

• Background:

  Function:Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta (5-73) shows a highly enhanced hematopoietic activity., online information:CXCL2 entry, pharmaceutical:GRO-beta (5-73) is available under the name Garnocestim as immunomodulator. It is used prior to hematopoietic transplantation for peripheral blood stem cell mobilization and reduction of incidence, duration, and/or severity of chemotherapy induced cytopenias., PTM:The N-terminal processed form GRO-beta (5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells., similarity:Belongs to the intercrine alpha (chemokine CxC) family.

• Description:

  Function: Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta (5-73) shows a highly enhanced hematopoietic activity. online information: CXCL2 entry, pharmaceutical: GRO-beta (5-73) is available under the name Garnocestim as immunomodulator. It is used prior to hematopoietic transplantation for peripheral blood stem cell mobilization and reduction of incidence, duration, and/or severity of chemotherapy induced cytopenias. PTM: The N-terminal processed form GRO-beta (5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells. similarity: Belongs to the intercrine alpha (chemokine CxC) family.

• Synonyms:

  C-X-C motif chemokine 2 (Growth-regulated protein beta;Gro-beta;Macrophage inflammatory protein 2-alpha;MIP2-alpha) [Cleaved into: GRO-beta(5-73;GRO-beta-T;Hematopoietic synergistic factor;HSF;SB-251353)]

• Gene ID:

  2920

• UniProt:

  P19875

• Cellular Locus:

  Secreted.

• Host:

  Rabbit

• Species Reactivity:

  Human, Rat, Mouse,

• Reactivity:

  Human; Rat; Mouse

• Immunogen:

  Synthesized peptide derived from human GROβ AA range: 58-107

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB, ELISA

• Validated Applications:

  WB, ELISA

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:1000-2000 ELISA 1:5000-20000

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Subcellular Location:

  Secreted.

• Other Product Names:

  C-X-C motif chemokine 2 (Growth-regulated protein beta; Gro-beta; Macrophage inflammatory protein 2-alpha; MIP2-alpha) [Cleaved into: GRO-beta (5-73; GRO-beta-T; Hematopoietic synergistic factor; HSF; SB-251353) ]

• Gene ID (Human):

  2920

• SwissProt (Human):

  P19875