Fluorescent DOTAP

CAT: 0804-HY-143702-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-143702-01Size:1 mg
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Description
Fluorescent DOTAP (NBD-DOTAP) is a cationic lipid which can be used for nucleic acid and protein delivery. Fluorescent DOTAP is labeled with a fluorophore NBD (maximum excitation/emission wavelength ∼463/536 nm) . Fluorescent DOTAP can be used for gene delivery systems, drug delivery, as well as cell imaging and nanocarrier tracking. Fluorescent DOTAP is an ideal candidate for both biological and pharmaceutical formulation (e.g. co-delivery of vaccines) research[1][3].
CAS Number
[1010076-97-7]
Product Name Alternative
NBD-DOTAP
UNSPSC
12352200
Target
Fluorescent Dye; Liposome
Type
Biochemical Assay Reagents
Related Pathways
Metabolic Enzyme/Protease; Others
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/fluorescent-dotap.html
Purity
98.00
Solubility
DMSO : 20 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CCCCCCCC/C=C\CCCCCCCC(OCC(OC(CCCCCNC1=CC=C([N+]([O-])=O)C2=NON=C21)=O)C[N+](C)(C)C)=O.[Cl-]
Molecular Formula
C36H60ClN5O7
Molecular Weight
710.34
References & Citations
[1]Simberg, D., et al., (2004) . DOTAP (and other cationic lipids) : chemistry, biophysics, and transfection. Critical reviews in therapeutic drug carrier systems, 21 (4), 257-317.|[2]Matos, A. L. L., et al., (2017) . Delivery of cationic quantum dots using fusogenic liposomes in living cells. Journal of photochemistry and photobiology. B, Biology, 171, 43-49.|[3]Chen, W., et al., (2008) . A simple but effective cancer vaccine consisting of an antigen and a cationic lipid. Cancer immunology, immunotherapy : CII, 57 (4), 517-530.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported

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