Fluorescent DOTAP

• Description :

  Fluorescent DOTAP (NBD-DOTAP) is a cationic lipid which can be used for nucleic acid and protein delivery. Fluorescent DOTAP is labeled with a fluorophore NBD (maximum excitation/emission wavelength ∼463/536 nm) . Fluorescent DOTAP can be used for gene delivery systems, drug delivery, as well as cell imaging and nanocarrier tracking. Fluorescent DOTAP is an ideal candidate for both biological and pharmaceutical formulation (e.g. co-delivery of vaccines) research[1][3].

• Product Name Alternative :

  NBD-DOTAP

• UNSPSC :

  12352200

• Target :

  Fluorescent Dye; Liposome

• Type :

  Biochemical Assay Reagents

• Related Pathways :

  Metabolic Enzyme/Protease; Others

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Cancer; Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/fluorescent-dotap.html

• Purity :

  98.00

• Solubility :

  DMSO : 20 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles :

  CCCCCCCC/C=C\CCCCCCCC(OCC(OC(CCCCCNC1=CC=C([N+]([O-])=O)C2=NON=C21)=O)C[N+](C)(C)C)=O.[Cl-]

• Molecular Formula :

  C36H60ClN5O7

• Molecular Weight :

  710.34

• References & Citations :

  [1]Simberg, D., et al., (2004) . DOTAP (and other cationic lipids) : chemistry, biophysics, and transfection. Critical reviews in therapeutic drug carrier systems, 21 (4), 257-317.|[2]Matos, A. L. L., et al., (2017) . Delivery of cationic quantum dots using fusogenic liposomes in living cells. Journal of photochemistry and photobiology. B, Biology, 171, 43-49.|[3]Chen, W., et al., (2008) . A simple but effective cancer vaccine consisting of an antigen and a cationic lipid. Cancer immunology, immunotherapy : CII, 57 (4), 517-530.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light, stored under nitrogen)

• Scientific Category :

  Biochemical Assay Reagents

• Clinical Information :

  No Development Reported

• CAS Number :

  [1010076-97-7]