JNK-IN-18

• UNSPSC Description:

  JNK-IN-18 (compund 23b) is a JNK1 inhibitor with IC50 of 2 nM, compared to JNK2 and BRAF(V600E) with IC50 of 125 nM and 98 nM, respectively[1].

• Target Antigen:

  JNK

• Type:

  Reference compound

• Related Pathways:

  MAPK/ERK Pathway

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/jnk-in-18.html

• Smiles:

  O=S(C1=CC=C(F)C=C1)(NCCCNC2=NC=CC(C3=CN(CC)N=C3C4=CC=CC(O)=C4)=C2)=O

• Molecular Weight:

  495.57

• References & Citations:

  [1]https://www.sciencedirect.com/science/article/abs/pii/S0045206824007302

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported