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JNK-IN-14

CAT: 0931-T79754-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T79754-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
JNK, Cytochromes P450
Related Pathways
Metabolism, MAPK
Bioactivity
JNK-IN-14 is a potent inhibitor of JNK with IC50 values of 1.81 nM for JNK1, 12.7 nM for JNK2, and 10.5 nM for JNK3. It induces early-stage apoptosis, arrests cell population at the G2/M phase, and moderately inhibits beclin-1 production in K562 leukemia cells, demonstrating greater inhibitory efficacy than SP600125. [1]
Molecular Formula
C27H31N5O4S
Molecular Weight
521.63
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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