Zosurabalpin (TFA)

• UNSPSC Description:

  Zosurabalpin TFA is a tethered macrocyclic peptide antibiotic, acting specifically on A. baumannii. Zosurabalpin TFA inhibits lipopolysaccharide-transport[1].

• Target Antigen:

  Antibiotic; Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  infection

• Assay Protocol:

  https://www.medchemexpress.com/zosurabalpin-tfa.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1NCC2=C(C3=CC=C(C=C3)C(O)=O)C=CC=C2SC4=NC=CC=C4CN[C@H](C(N[C@H](C(N([C@H]1CC5=CNC6=CC=CC=C56)C)=O)CCCCN)=O)CCCN.OC(C(F)(F)F)=O.[x]

• Molecular Weight:

  790.97 (free base)

• References & Citations:

  [1]Karanbir S Pahil, et al. A new antibiotic traps lipopolysaccharide in its intermembrane transporter. Nature. 2024 Jan;625(7995):572-577.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported