SHMT2 Antibody

• Gene Name:

  Serine hydroxymethyltransferase 2

• Gene Aliases:

  GLYA, SHMT, NEDCASB, HEL-S-51e

• Gene ID:

  6472

• Accession Number:

  NP_001159828.1

• Reactivity:

  Human

• Immunogen:

  Recombinant protein encompassing a sequence within the N-terminus region of human SHMT2. The exact sequence is proprietary.

• Target:

  This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing results in multiple transcript variants.

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Applications:

  ICC, IF, IHC-P, WB

• Purification:

  Purified by antigen-affinity chromatography.

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  1 mg/ml

• Format:

  Liquid

• Buffer:

  1XPBS, 20% Glycerol (pH7) . 0.01% Thimerosal was added as a preservative.

• Reconstitution:

  Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

• Fragment:

  IgG

• NCBI Gene Symbol:

  SHMT2

• Host or Source:

  Rabbit

• Protein Name:

  Serine hydroxymethyltransferase, mitochondrial

• Gene Name URL:

  SHMT2

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_001166356.1