SHMT1 Antibody

• Gene Name :

  Serine hydroxymethyltransferase 1 (soluble)

• Gene Aliases :

  SHMT, CSHMT

• Gene ID :

  6470

• Swiss Prot :

  P34896

• Accession Number :

  NP_683718

• Reactivity :

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

• Immunogen :

  The immunogen is a synthetic peptide directed towards the following sequence LVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALT

• Target :

  This gene encodes the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing of this gene results in 2 transcript variants encoding 2 different isoforms. Additional transcript variants have been described, but their biological validity has not been determined.

• Partner Proteins :

  UBC; SULT1A3; SHMT1; MAPK9; C18orf25; FAM129B; SNX6; XPO5; VPS29; PBDC1; GSPT2; HIST1H4A; CARS; ATP6V1C1; APEH; CTTN; TTC1; TSN; STAT1; SNX2; SHMT2; PAWR; IDE; HARS; GTF2F2; GARS; DEDD; MCAT; ZC3H4; HSPA1L; SUMO1; SUMO2; SUMO3; PRSS23; PIM1; CSNK2B; DLEU1

• Clonality :

  Polyclonal

• Type :

  Polyclonal Antibody

• Sequence :

  LVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALT

• Purification :

  Affinity Purified

• Assay Protocol :

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration :

  0.5 mg/ml

• Homology :

  Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 93%

• Format :

  Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Reconstitution :

  For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

• Molecular Weight :

  53 kDa

• Protein Length :

  483

• NCBI Gene Symbol :

  SHMT1

• Host or Source :

  Rabbit

• Protein Name :

  Serine hydroxymethyltransferase, cytosolic

• Gene Name URL :

  SHMT1

• CAS Number :

  9007-83-4

• Nucleotide Accession Number :

  NM_004169