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SHMT1 Antibody

CAT: 0247-ARP49041_P050-25ULSize: 25 µLDry Ice: NoHazardous: No
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CAT#:0247-ARP49041_P050-25ULSize:25 µL
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CAS Number
9007-83-4
Gene Name
Serine hydroxymethyltransferase 1 (soluble)
Gene Aliases
SHMT, CSHMT
Gene ID
6470
Swiss Prot
P34896
Accession Number
NP_683718
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the following sequence LVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALT
Target
This gene encodes the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing of this gene results in 2 transcript variants encoding 2 different isoforms. Additional transcript variants have been described, but their biological validity has not been determined.
Partner Proteins
UBC; SULT1A3; SHMT1; MAPK9; C18orf25; FAM129B; SNX6; XPO5; VPS29; PBDC1; GSPT2; HIST1H4A; CARS; ATP6V1C1; APEH; CTTN; TTC1; TSN; STAT1; SNX2; SHMT2; PAWR; IDE; HARS; GTF2F2; GARS; DEDD; MCAT; ZC3H4; HSPA1L; SUMO1; SUMO2; SUMO3; PRSS23; PIM1; CSNK2B; DLEU1
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
LVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALT
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
53 kDa
Protein Length
483
NCBI Gene Symbol
SHMT1
Host or Source
Rabbit
Protein Name
Serine hydroxymethyltransferase, cytosolic
Gene Name URL
SHMT1
Nucleotide Accession Number
NM_004169

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