RUNX1T1 Antibody

• Gene Name:

  RUNX1 partner transcriptional co-repressor 1

• Gene Aliases:

  Acute myelogenous leukemia 1 translocation 1, cyclin-D related; AML1-MTG8; AML1T1; CBFA2T1; CDR; core-binding factor, runt domain, alpha subunit 2; translocated to, 1; cyclin D-related; Cyclin-D-related protein; eight twenty one protein; ETO; MTG8; myeloid translocation gene on 8q22; protein CBFA2T1; Protein ETO; Protein MTG8; runt related transcription factor 1; translocated to, 1 (cyclin D related) ; RUNX1 translocation partner 1; zinc finger MYND domain-containing protein 2; ZMYND2.

• Gene ID:

  862

• Accession Number:

  NP_001185554

• Reactivity:

  Human

• Immunogen:

  Recombinant Human Protein CBFA2T1 protein (416-525AA)

• Target:

  Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes (PubMed:12559562, PubMed:15203199) . Can repress the expression of MMP7 in a ZBTB33-dependent manner (PubMed:23251453) . Can repress transactivation mediated by TCF12 (PubMed:16803958) . Acts as a negative regulator of adipogenesis (By similarity) . The AML1-MTG8/ETO fusion protein frequently found in leukemic cells is involved in leukemogenesis and contributes to hematopoietic stem/progenitor cell self-renewal (PubMed:23812588) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot

• Purification:

  Protein G Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Format:

  Liquid

• Reconstitution:

  -20°C or -80°C

• Fragment:

  IgG

• NCBI Gene Symbol:

  RUNX1T1

• Host or Source:

  Rabbit

• Protein Name:

  Protein CBFA2T1

• Gene Name URL:

  RUNX1T1

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_001198625