TOB1 Antibody (Phospho-Ser164)

CAT: 0247-OAAF00578-100UGSize: 100 µgDry Ice: NoHazardous: No
CAT#:0247-OAAF00578-100UGSize:100 µg
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CAS Number
9007-83-4
Gene Name
Transducer of ERBB2, 1
Gene Aliases
APRO5; APRO6; PIG49; proliferation-inducing gene 49; protein Tob1; TOB; transducer of erbB-2 1; TROB; TROB1.
Gene ID
10140
Swiss Prot
P50616
Accession Number
NP_001230806.1
Reactivity
Human|Mouse|Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human TOB1 around the phosphorylation site of Ser164.
Target
Anti-proliferative protein; the function is mediated by association with deadenylase subunits of the CCR4-NOT complex (PubMed:8632892, PubMed:23236473) . Mediates CPEB3-accelerated mRNA deadenylation by binding to CPEB3 and recruiting CNOT7 which leads to target mRNA deadenylation and decay (PubMed:21336257) .
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Dilution
The optimal working dilution should be determined by the end user.
Format
Liquid
Reconstitution
-20°C
Molecular Weight
38 kDa
Notes
Formerly GWB-ASC018
Specificity
TOB1 (Phospho-Ser164) antibody detects endogenous levels of TOB1 only when phosphorylated at serine 164.
NCBI Gene Symbol
TOB1
Host or Source
Rabbit
Protein Name
Protein Tob1
Gene Name URL
TOB1

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