Pasireotide Acetate

• Target:

  Somatostatin

• Related Pathways:

  GPCR/G Protein

• Purity:

  0.9992

• Bioactivity:

  Pasireotide (SOM230) acetate is a long-acting cyclohexapeptide growth hormone inhibitory hormone analog with antisecretory, antiproliferative, and proapoptotic activities.Pasireotide (SOM230) acetate inhibits the secretion of GH, IGF-I, and ACTH, and can be used in the study of acromegaly and Cushing's disease. Pasireotide (SOM230) acetate also enhances the agonist activity of growth inhibitory receptors, with pKi of 8.2, 9.0, 9.1, <7.0 and 9.9 for sst1, 2, 3, 4 and 5, respectively.

• Smiles:

  CC (O) =O.NCCCC[C@@H]1NC (=O) [C@@H] (Cc2c[nH]c3ccccc23) NC (=O) [C@@H] (NC (=O) [C@@H]2C[C@H] (CN2C (=O) [C@H] (Cc2ccccc2) NC (=O) [C@H] (Cc2ccc (OCc3ccccc3) cc2) NC1=O) OC (=O) NCCN) c1ccccc1

• Molecular Formula:

  C60H70N10O11

• Molecular Weight:

  1107.26

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  396091-76-2