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YAP-TEAD-IN-2

CAT: 0013-GTR19219606-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19219606-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
YAP-TEAD-IN-2 (compound 6) is a highly potent, nanomolar-range inhibitor of the YAP-TEAD protein-protein interaction, with an IC50 of 2.7 nM. This small molecule is a valuable chemical probe for fundamental research into the Hippo signaling pathway and has been utilized in both in vitro and in vivo cancer models to study oncogenic transcription driven by this PPI.
CAS Number
2714432-83-2
Field of Research
Cancer Biology, Stem Cell & Developmental Biology
Smiles
O=C (C1=CC=C (C (F) =C1C2=C3C[C@@] (C4=CC=CC=C4) (CN) OC3=CC=C2Cl) OCCOC) N
Molecular Formula
C25H24ClFN2O4
Molecular Weight
470.92
Storage Conditions
-20°C
Notes
For research use only.

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