AMY-101

CAT: 0931-MF-0062802-01Size: 100 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0062802-01Size:100 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1427001-89-5
Target
SARS-CoV|||Others|||Complement System
Related Pathways
Microbiology/Virology|||Immunology/Inflammation|||Others
Bioactivity
AMY-101 is a peptidic inhibitor of the central complement component C3 (KD: 0.5 nM) . AMY-101 shows a favorable anti-inflammatory activity in models with COVID-19 severe pneumonia with systemic hyper inflammation.
Smiles
CC[C@H](C)[C@H](NC(=O)[C@H](N)Cc1ccc(O)cc1)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](C)NC(=O)CN(C)C(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc2cn(C)c3ccccc23)NC(=O)[C@@H](NC1=O)C(C)C)C(=O)N(C)[C@@H]([C@@H](C)CC)C(N)=O
Molecular Formula
C83H117N23O18S2
Molecular Weight
1789.11
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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MBS5789532AMY-101
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A22779-5AMY-101 TFA 5mg
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