UFP-101

• Target:

  Opioid Receptor

• Related Pathways:

  Neuroscience|||Endocrinology/Hormones|||GPCR/G Protein

• Bioactivity:

  Potent, selective and competitive silent antagonist for the NOP opioid receptor. Binds to NOP with high affinity (pKi = 10.24) and displays > 3000-fold selectivity over ?, ? and ? opioid receptors. Antinociceptive and opposes the action of nociceptin in vivo.

• Smiles:

  [C@H](CC1=CC=CC=C1)(C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCC(N)=O)C(N)=O)=O)CC(N)=O)=O)CCCCN)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCNC(=N)N)=O)C)=O)CO)=O)CCCCN)=O)CCCNC(=N)N)=O)C)=O)=O)[C@@H](C)O)=O)NC(CNC(CNC(CNCC2=CC=CC=C2)=O)=O)=O

• Molecular Formula:

  C82H138N32O21

• Molecular Weight:

  1908.19

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  849024-68-6