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TAT-Gap19

CAT: 0931-TP2110Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-TP2110Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1507930-54-2
Target
Gap Junction Protein
Related Pathways
Cytoskeletal Signaling
Bioactivity
Cx43 hemichannel blocker (IC50 ~7 ?M) . No significant affinity for gap junctions or Panx1 channels. N-terminal transactivator of transcription (TAT) motif promotes membrane permeability and increases inhibitory effect of Gap19. Active in vivo. Brain penetrant.
Smiles
[C@@H](CC1=CC=CC=C1)(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H](CC2=CC=C(O)C=C2)N)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCCN)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCCN)=O)CCC(N)=O)=O)[C@H](CC)C)=O)CCC(O)=O)=O)[C@H](CC)C)=O)CCCCN)=O)CCCCN)=O)C(N[C@@H](CCCCN)C(O)=O)=O
Molecular Formula
C119H212N46O26
Molecular Weight
2703.28
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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