UFP-803

• Target:

  GPCR

• Related Pathways:

  GPCR/G Protein|||Endocrinology/Hormones

• Bioactivity:

  Urotensin-II (UT) receptor ligand; behaves as a silent antagonist in most in vitro assays and in vivo, but does retain small residual agonist activity under certain conditions in some assays. Competitively antagonizes U-II induced contractions in the rat aorta (pIC50 = 7.46) and prevents plasma extravasation elicited by U-II in mice in vivo.

• Smiles:

  C (C=1C=2C (NC1) =CC=CC2) [C@H]3NC (=O) [C@H] (CC4=CC=CC=C4) NC (=O) [C@@H] (NC ([C@H] (CC (O) =O) N) =O) C (C) (C) SSC[C@@H] (C (N[C@@H] (C (C) C) C (O) =O) =O) NC (=O) [C@H] (CC5=CC=C (O) C=C5) NC (=O) [C@H] (CCN) NC3=O

• Molecular Formula:

  C50H64N10O12S2

• Molecular Weight:

  1061.24

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  879497-82-2