UFP-803

• Target:

  GPCR

• Related Pathways:

  GPCR/G Protein|||Endocrinology/Hormones

• Bioactivity:

  Urotensin-II (UT) receptor ligand; behaves as a silent antagonist in most in vitro assays and in vivo, but does retain small residual agonist activity under certain conditions in some assays. Competitively antagonizes U-II induced contractions in the rat aorta (pIC50 = 7.46) and prevents plasma extravasation elicited by U-II in mice in vivo.

• Smiles:

  C(C=1C=2C(NC1)=CC=CC2)[C@H]3NC(=O)[C@H](CC4=CC=CC=C4)NC(=O)[C@@H](NC([C@H](CC(O)=O)N)=O)C(C)(C)SSC[C@@H](C(N[C@@H](C(C)C)C(O)=O)=O)NC(=O)[C@H](CC5=CC=C(O)C=C5)NC(=O)[C@H](CCN)NC3=O

• Molecular Formula:

  C50H64N10O12S2

• Molecular Weight:

  1061.24

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  879497-82-2