[Ala17]-MCH acetate

CAT: 0931-MF-0046003-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0046003-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Melanin-concentrating Hormone Receptor (MCHR)
Related Pathways
GPCR/G Protein
Purity
0.9892
Bioactivity
[Ala17]-MCH acetate is a selective ligand for MCHR1 with a Ki of 0.16 nM and Kd of 0.37 nM (Eu3+ chelate-labeled) . [Ala17]-MCH acetate shows selectivity over MCHR2 with Ki of 34 nM.
Smiles
O=C1N2[C@](CCC2)([H])C(N[C@@H](CSSC[C@@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]1CCCNC(N)=N)=O)CC3=CC=C(C=C3)O)=O)C(C)C)=O)CCCNC(N)=N)=O)=O)CC(C)C)=O)CCSC)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@H](CCSC)NC([C@H](CC(O)=O)NC([C@@H](NC([C@@H](N)CC(O)=O)=O)CC4=CC=CC=C4)=O)=O)=O)=O)=O)C(N[C@@H](C)C(N[C@@H](CCC(N)=O)C(N[C@H](C(O)=O)C(C)C)=O)=O)=O)=O.CC(O)=O
Molecular Formula
C99H159N29O28S4
Molecular Weight
2331.76
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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