PG 106 acetate

• Target:

  Melanocortin Receptor

• Related Pathways:

  GPCR/G Protein|||Neuroscience

• Purity:

  0.9824

• Bioactivity:

  PG 106 acetate is an effective and selective antagonist of the human melanocortin 3 (hMC3) receptor with an IC50 of 210 nM. PG 106 acetate has no activity with the hMC5 receptor and hMC4 receptors with an EC50 of 9900 nM.

• Smiles:

  CCCCC (NC (C) =O) C (N[C@H]1CC (NCCCC[C@@H] (C (N) =O) NC ([C@H] (CC2=CNC3=CC=CC=C32) NC ([C@H] (CCC/N=C (N) \N) NC ([C@@H] (CC4=CC5=CC=CC=C5C=C4) NC (CCNC1=O) =O) =O) =O) =O) =O) =O.CC (O) =O

• Molecular Formula:

  C53H73N13O11

• Molecular Weight:

  1068.23

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C