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RAGE antagonist peptide

CAT: 0931-TP1935Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-TP1935Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1092460-91-7
Target
Beta Amyloid
Related Pathways
Neuroscience
Bioactivity
Receptor for advanced glycation end products (RAGE) antagonist. Blocks S100P, S100A4 and HMGB-1 mediated RAGE activation in vitro and in vivo. Inhibits growth and metastasis of rat glioma tumors. Reduces cell growth and RAGE-mediated NF-κB activity in human PDAC cell lines. Inhibits effects of TDI exposure in BALB/c mice.
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[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(N)=O)=O)CCC(O)=O)=O)CCCCN)=O)(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCC(O)=O)NC(C)=O)=O)CC(C)C)=O)CCCCN)=O)[C@H](C)C)=O)CC(C)C)=O)CCSC)=O)CCC(O)=O
Molecular Formula
C57H101N13O17S
Molecular Weight
1272.56
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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