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Cucurbitacin D

CAT: 0931-TN1013-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-TN1013-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3877-86-9
Target
Apoptosis|||HSP
Related Pathways
Apoptosis|||Cytoskeletal Signaling|||Metabolism
Purity
0.991
Bioactivity
Cucurbitacin D, a triterpenoid isolated from Ecballium elaterium (L.), exhibits anticancer and antitumor activity, inhibits glucose uptake and lactate production in metastatic PrC, and induces inflammasome activation independent of ERK1/2 activation. Cucurbitacin D, a novel inflammasome activator in macrophages, inhibits HepG2 cell proliferation and induces apoptosis by modulating the JAK/STAT3, PI3K/Akt/mTOR and MAPK signaling pathways, and can be used in the study of cervical cancer, leukemia, and prostate cancer.
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CC(C)(O)\C=C\C(=O)[C@](C)(O)[C@H]1[C@H](O)C[C@@]2(C)[C@@H]3CC=C4[C@@H](C[C@H](O)C(=O)C4(C)C)[C@]3(C)C(=O)C[C@]12C
Molecular Formula
C30H44O7
Molecular Weight
516.67
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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