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Cucurbitacin IIA

CAT: 0931-T3S1471-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T3S1471-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
58546-34-2
Target
Survivin, Apoptosis
Related Pathways
Apoptosis
Purity
0.9987
Bioactivity
1. Cucurbitacin IIA (Dihydrocucurbitacin Q1) can induce apoptosis and enhance autophagy , contributes to the anti-inflammatory activity of Cucurbitacin IIA against inflammation-related diseases. 2. Cucurbitacin IIA is a novel class of anti-cancer drug in suppression of cancer cell expansion by disrupting the actin cytoskeleton and directing the cell to undergo PARP-mediated apoptosis through the inhibition of survivin downstream of JAK2/STAT3.
Smiles
[H][C@@]1([C@H](O)C[C@@]2(C)[C@]3([H])CC=C4[C@@]([H])(C[C@H](O)[C@@H](O)C4(C)C)[C@]3(C)C(=O)C[C@]12C)[C@@](C)(O)C(=O)CCC(C)(C)OC(C)=O
Molecular Formula
C32H50O8
Molecular Weight
562.73
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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