Cucurbitacin A

• Target :

  ROCK

• Related Pathways :

  Cytoskeletal Signaling|||Stem Cells|||Cell Cycle/Checkpoint

• Bioactivity :

  Cucurbitacin I, cytotoxic triterpenoid sterols isolated from plants, elicits the formation of actin/phospho-myosin II co-aggregates by stimulation of the RhoA/ROCK pathway and inhibition of LIM-Kinase.

• Smiles :

  [H][C@@]12C[C@H](O)C(=O)C(C)(C)C1=CC[C@@]1([H])[C@]3(C)C[C@@H](O)[C@H]([C@@](C)(O)C(=O)\C=C\C(C)(C)OC(C)=O)[C@@]3(C)CC(=O)[C@@]21CO

• Molecular Formula :

  C32H46O9

• Molecular Weight :

  574.7

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  6040-19-3