YH-53

• Target:

  Others|||SARS-CoV

• Related Pathways:

  Others|||Microbiology/Virology

• Bioactivity:

  YH-53 is a potent 3CLpro inhibitor, exhibiting K i values of 6.3 nM and 34.7 nM against SARS-CoV-1 3CLpro and SARS-CoV-2 3CLpro, respectively. This peptidomimetic compound, characterized by its unique benzothiazolyl ketone structure, significantly inhibits SARS-CoV-2 replication, highlighting its potential in COVID-19 research [1] [2].

• Smiles:

  COc1cccc2[nH]c (cc12) C (=O) N[C@@H] (CC (C) C) C (=O) N[C@@H] (C[C@@H]1CCNC1=O) C (=O) c1nc2ccccc2s1

• Molecular Formula:

  C30H33N5O5S

• Molecular Weight:

  575.68

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1471484-62-4