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YH-53

CAT: 0931-T9686-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T9686-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1471484-62-4
Target
Others, SARS-CoV
Related Pathways
Others, Microbiology/Virology
Bioactivity
YH-53 is a potent 3CLpro inhibitor, exhibiting K i values of 6.3 nM and 34.7 nM against SARS-CoV-1 3CLpro and SARS-CoV-2 3CLpro, respectively. This peptidomimetic compound, characterized by its unique benzothiazolyl ketone structure, significantly inhibits SARS-CoV-2 replication, highlighting its potential in COVID-19 research [1] [2].
Smiles
COc1cccc2[nH]c(cc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)c1nc2ccccc2s1
Molecular Formula
C30H33N5O5S
Molecular Weight
575.68
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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