PMX-53

CAT: 0931-T28429Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T28429Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
219639-75-5
Target
Complement System
Related Pathways
Immunology/Inflammation
Bioactivity
PMX-53 is a Mas-related gene 2 (MrgX2) agonist and C5aR (CD88) antagonist. PMX-53 reduces atherosclerotic lesions in a mouse model of atherosclerosis, inhibits lung metastasis in a mouse breast cancer model, inhibits C5a-induced hypernociception in rats.
Smiles
CC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H]1CCCNC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](CC2CCCCC2)NC(=O)[C@@H]2CCCN2C1=O
Molecular Formula
C47H65N11O7
Molecular Weight
896.09
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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