BAY-8400

• Target:

  DNA-PK

• Related Pathways:

  PI3K/Akt/mTOR signaling|||DNA Damage/DNA Repair

• Purity:

  0.9953

• Bioactivity:

  BAY-8400 is a potent, selective, and orally active DNA-dependent protein kinase (DNA-PK) inhibitor (IC50 = 81 nM) that demonstrates synergistic efficacy when combined with targeted alpha therapies. BAY-8400 is applicable for cancer research [1].

• Smiles:

  FC(F)C1=CN=CC(C2=CC=C(N=CC3=NN=C(C4=CCCOCC4)N35)C5=C2)=C1

• Molecular Formula:

  C21H17F2N5O

• Molecular Weight:

  393.39

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C