BAY-677

• Target :

  Others|||Serine Protease

• Related Pathways :

  Others|||Proteases/Proteasome

• Bioactivity :

  BAY-677, serving as an inactive control for BAY-678, is distinguished by BAY-678's capabilities as an orally bioavailable, selective, and cell-permeable inhibitor of human neutrophil elastase (HNE), showcasing a high potency with an IC50 of 20 nM[1]. Furthermore, BAY-678 has been publicly nominated as a chemical probe by the Structural Genomics Consortium (SGC) [2].

• Smiles :

  CC(=O)C1=C(C)N(C(=O)N[C@H]1c1ccc(nc1)C#N)c1cccc(c1)C(F)(F)F

• Molecular Formula :

  C20H15F3N4O2

• Molecular Weight :

  400.35

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2117404-84-7