BAY-677

CAT: 0931-MF-0004586Size: 2 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0004586Size:2 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2117404-84-7
Target
Others|||Serine Protease
Related Pathways
Others|||Proteases/Proteasome
Bioactivity
BAY-677, serving as an inactive control for BAY-678, is distinguished by BAY-678's capabilities as an orally bioavailable, selective, and cell-permeable inhibitor of human neutrophil elastase (HNE), showcasing a high potency with an IC50 of 20 nM[1]. Furthermore, BAY-678 has been publicly nominated as a chemical probe by the Structural Genomics Consortium (SGC) [2].
Smiles
CC(=O)C1=C(C)N(C(=O)N[C@H]1c1ccc(nc1)C#N)c1cccc(c1)C(F)(F)F
Molecular Formula
C20H15F3N4O2
Molecular Weight
400.35
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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MBS3844290-01BAY-677
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A19838-25BAY-677 25mg
A19838-50BAY-677 50mg
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A19838-100BAY-677 100mg
A19838-10BAY-677 10mg
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