CHIKV-IN-2

• Target:

  Anti-infection|||Dehydrogenase

• Related Pathways:

  Microbiology/Virology|||Metabolism

• Purity:

  0.9867

• Bioactivity:

  CHIKV-IN-2, a chemical compound, exhibits potent inhibitory activity against the enzyme Dihydroorotate Dehydrogenase (DHODH), crucial for pyrimidine synthesis affecting various viruses' replication. It serves as an effective Chikungunya virus (CHIKV) inhibitor, demonstrating significant cellular antiviral activity (EC90=270 nM) and enhanced liver microsomal stability[1].

• Smiles:

  COc1cc2CCCCCc2cc1C (=O) Nc1ccc (cc1) C (C) (C) C#N

• Molecular Formula:

  C23H26N2O2

• Molecular Weight:

  362.46

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2361289-44-1