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CHIKV nsP2 protease-IN-2

CAT: 0931-T211694-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T211694-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Virus Protease
Related Pathways
Microbiology/Virology
Bioactivity
CHIKV nsP2 protease-IN-2 (Compound 2o) is an allosteric inhibitor of the non-structural protein 2 helicase (nsP2hel), with IC50 values of 0.5 μM for nsP2 ATPase and 0.9 μM for RNA helicase. It exhibits broad-spectrum antiviral activity against alphaviruses, effectively targeting Chikungunya virus (CHIKV), Mayaro virus (MAYV), and Venezuelan equine encephalitis virus (VEEV), with an EC50 of 0.12 μM against CHIKV-nLuc. This compound is useful for research on alphavirus infections.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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