MM-102

• Target:

  TNF|||Interleukin|||Histone Methyltransferase|||NF-?B|||Apoptosis

• Related Pathways:

  Chromatin/Epigenetic|||NF-?B|||Immunology/Inflammation|||Apoptosis

• Purity:

  0.9999

• Bioactivity:

  MM-102 (HMTase Inhibitor IX) is a potent inhibitor of WDR5/MLL interaction with IC50 of 2.4 nM and Ki of less than 1 nM in a WDR5 binding assay. MM-102 can also specifically inhibit cell growth and induce apoptosis in leukemia cells carrying MLL1 fusion protein.

• Smiles:

  C(NC(C1=CC=C(F)C=C1)C2=CC=C(F)C=C2)(=O)C3(NC([C@@H](NC(C(NC(C(C)C)=O)(CC)CC)=O)CCCNC(=N)N)=O)CCCC3

• Molecular Formula:

  C35H49F2N7O4

• Molecular Weight:

  669.8

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1417329-24-8