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Theliatinib

CAT: 0931-T7322-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T7322-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1353644-70-8
Target
EGFR
Related Pathways
Tyrosine Kinase/Adaptors, JAK/STAT signaling, Angiogenesis
Purity
0.9967
Bioactivity
Theliatinib, a potent and highly selective EGFR inhibitor, with anti-tumor activity. Ki of 0.05 nM for wild type EGFR, and IC50s of 3 and 22 nM for EGFR and EGFR T790M/L858R mutant, respectively.
Smiles
[H][C@]12CCN(C)[C@@]1([H])CN(C2)C(=O)Nc1cc2c(Nc3cccc(c3)C#C)ncnc2cc1OC
Molecular Formula
C25H26N6O2
Molecular Weight
442.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C