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Cyclo (RGDfK)

CAT: 0013-GTR19157085-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19157085-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cyclo (RGDfK) is a synthetic lipopeptide inhibitor of αvβ3 integrin (IC50 = 1.33 nM) . Osteoblast cultures, which express αvβ5 and αvβ3 integrins, but not M21L cells that do not express these integrins, bind to cyclo (RGDfK) -coated surfaces. Cyclo (RGDfK) is taken up into tumors in vivo and in vitro and it has been polymerized or conjugated to various fluorophores, radiolabels, and peptide sequences for use in fluorescent and PET imaging to study tumor cell adhesion.
CAS Number
161552-3-0
Purity
>98% (HPLC)
Solubility
Water,100 mg/mL (139.34 mM)
Smiles
C1C (=O) NC (C (=O) NC (C (=O) NC (C (=O) NC (C (=O) N1) CCCN=C (N) N) CCCCN) CC2=CC=CC=C2) CC (=O) O.C (=O) (C (F) (F) F) O
Molecular Formula
C29H42F3N9O9
Molecular Weight
717.69
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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