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TDI-10229

CAT: 0931-T64355-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T64355-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2810887-45-5
Target
AChR, cAMP
Related Pathways
GPCR/G Protein, Neuroscience
Purity
0.9989
Bioactivity
TDI-10229 is a potent and orally available inhibitor of soluble adenylyl cyclase (sAC, ADCY10), displaying nanomolar inhibition of sAC in both biochemical and cellular assays (IC50 = 195 nM) . TDI-10229 exhibits mouse pharmacokinetic properties sufficient to warrant its use as an in vivo tool compound.
Smiles
Cc1c(Cc2ccccc2)c(nn1C)-c1cc(Cl)nc(N)n1
Molecular Formula
C16H16ClN5
Molecular Weight
313.78
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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